AffiAAV® rAAV-CMV-WPRE-hGH polyA

rAAV-CMV-WPRE-hGH polyA

rAAV-CMV-WPRE-hGH polyA is a recombinant adeno-associated virus (rAAV) vector designed for targeted gene delivery. Here are the key components and features:

• Cytomegalovirus Promoter (CMV): Drives strong, ubiquitous expression in a variety of cell types.
• WPRE (Woodchuck Hepatitis Virus Post-transcriptional Regulatory Element): Enhances transgene expression.
• hGH polyA (Human Growth Hormone Polyadenylation Signal): Ensures proper termination of transcription.

Application of rAAV-CMV-WPRE-hGH polyA

This rAAV vector is primarily used in research for robust gene expression in a wide range of cell types and tissues. The CMV promoter ensures high levels of expression, making it suitable for various gene therapy and research applications.

Advantage of rAAV-CMV-WPRE-hGH polyA

The combination of the CMV promoter and WPRE allows for high-level expression of the transgene, with the hGH polyA signal ensuring proper transcription termination. This vector is a versatile tool for gene therapy and research, providing strong and widespread expression of the desired gene.

Detailed Applications of rAAV-CMV-WPRE-hGH polyA

1. Gene Therapy:
   • Facilitates the delivery of therapeutic genes to a wide range of tissues.
   • Suitable for treating genetic disorders by providing high levels of the therapeutic protein.
2. Protein Production:
   • Enables high-level production of recombinant proteins in various cell types.
   • Useful for producing proteins for research, industrial, or therapeutic purposes.
3. Functional Studies:
   • Allows for the study of gene function by overexpressing the gene of interest in different cell types.
   • Useful for investigating the effects of gene overexpression on cellular and physiological processes.
4. Disease Models:
   • Can be used to create models of diseases by overexpressing disease-related genes.
   • Useful in preclinical research for understanding disease mechanisms and testing potential therapies.
5. Vaccination:
   • Can be used to deliver antigens for vaccine development.
   • Suitable for generating strong immune responses against target pathogens.