rAAV-hSyn

The hSyn promoter, derived from the human synapsin 1 gene, is a neuron-specific promoter commonly used in recombinant adeno-associated virus (rAAV) systems. Its specificity for neurons makes it a widely used tool for studying and manipulating neural circuits and functions.

Features of rAAV-hSyn
  • Neuron-Specific Expression:
    • The hSyn promoter drives transgene expression specifically in neurons, ensuring minimal off-target expression in glia or other cell types.
  • Broad Compatibility:
    • Functional across excitatory and inhibitory neurons in various species, including rodents, non-human primates, and humans.
  • High Expression:
    • Provides robust and consistent expression in neurons while maintaining cell-type specificity.
  • Long-Term Stability:
    • Enables sustained transgene expression, suitable for chronic studies.
Applications of rAAV-hSyn
  • Neuroscience Research:
    • Circuit Mapping: Expression of tracers or fluorescent proteins to study neural connectivity.
    • Optogenetics: Delivery of optogenetic tools (e.g., channelrhodopsins, halorhodopsins) for precise neural activation or silencing.
    • Calcium Imaging: Use of calcium indicators (e.g., GCaMP) to monitor neuronal activity.
  • Gene Therapy:
    • Experimental therapies targeting neurons for neurodegenerative diseases (e.g., Parkinson's, Alzheimer's) and other CNS disorders.
  • Behavioral Studies:
    • Manipulating specific neural circuits to investigate their role in behaviors, such as learning, memory, or motor control.
  • CRISPR/Cas9 Genome Editing:
    • Delivery of gene-editing components selectively to neurons for targeted gene modification.
  • Neurodegenerative Disease Modeling:
    • Introduction of disease-related genes or knockdown of neuronal genes to model disorders in vivo.

rAAV-hSyn is a powerful and reliable tool for neuron-specific gene delivery in neuroscience and gene therapy applications. Its broad applicability and strong, stable expression make it a preferred choice for studying and manipulating neural circuits and for developing targeted therapies for CNS disorders.

AffiAAV® rAAV-hSyn-fDIO-TagBFP-WPRE-hGH polyA
CAT# AFG-BRV-0274
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-fDIO-EGFP-WPREs
CAT# AFG-BRV-0272
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-fDIO-mCherry-WPRE-hGH polyA
CAT# AFG-BRV-0271
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-fDIO-EGFP-WPRE-hGH polyA
CAT# AFG-BRV-0270
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-fDIO-BFP-WPRE-hGH polyA
CAT# AFG-BRV-0269
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-DIO-mScarlet-WPREs
CAT# AFG-BRV-0207
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-DIO-3XFlag-P2A-EGFP-WPREs
CAT# AFG-BRV-0206
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-DIO-GFP-WPRE-hGH polyA
CAT# AFG-BRV-0203
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-DIO-mEGFP-WPRE-hGH polyA
CAT# AFG-BRV-0202
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-DIO-mCherry-WPRE-hGH polyA
CAT# AFG-BRV-0199
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-DIO-EYFP-WPRE-hGH polyA
CAT# AFG-BRV-0198
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-DIO-EGFP-WPRE-hGH polyA
CAT# AFG-BRV-0197
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-DO-EGFP-WPREs
CAT# AFG-BRV-0189
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-Coff Fon-EYFP-WPRE-hGH polyA
CAT# AFG-BRV-0177
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-Con Foff-EYFP-WPRE-hGH polyA
CAT# AFG-BRV-0175
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-Con/Fon-EYFP-WPRE-hGH polyA
CAT# AFG-BRV-0172
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-EYFP-WPRE-bGH polyA
CAT# AFG-BRV-0034
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-NLS mCherry-WPRE-hGH polyA
CAT# AFG-BRV-0033
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-NLS EGFP-WPRE-hGH polyA
CAT# AFG-BRV-0032
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-H2B-TagBFP-WPRE-hGH polyA
CAT# AFG-BRV-0031
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-EGFP-HA-WPRE-hGH polyA
CAT# AFG-BRV-0030
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-BFP-WPRE-hGH polyA
CAT# AFG-BRV-0029
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-EGFP-WPRE-hGH polyA
CAT# AFG-BRV-0028
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-mito-EGFP-WPRE-hGH polyA
CAT# AFG-BRV-0027
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-HA-hGH polyA
CAT# AFG-BRV-0026
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-tdTomato-WPRE-hGH polyA
CAT# AFG-BRV-0025
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-mEGFP-WPRE-hGH polyA
CAT# AFG-BRV-0024
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-mCherry-WPRE-hGH polyA
CAT# AFG-BRV-0023
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-Flag-WPRE-hGH polyA
CAT# AFG-BRV-0022
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-EGFP-3XFlag-WPRE-hGH polyA
CAT# AFG-BRV-0021
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-EYFP-WPRE-hGH polyA
CAT# AFG-BRV-0020
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-mCherry-WPRE-hGH polyA
CAT# AFG-BRV-0019
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-Jaws-tdTomato-WPRE-hGH polyA
CAT# AFG-BRV-1355
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-Jaws-EGFP-ER2-WPRE-pA
CAT# AFG-BRV-1354
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-ArchT-EGFP-WPRE-hGH polyA
CAT# AFG-BRV-1338
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-ARChT-tdTomato-WPRE-hGH polyA
CAT# AFG-BRV-1337
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-eNpHR3.0-EYFP-WPRE-hGH polyA
CAT# AFG-BRV-1282
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hsyn-DO-chrimsonR-Tdtomato-WPREs
CAT# AFG-BRV-1265
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-ChrimsonR-BFP-WPRE-hGH polyA
CAT# AFG-BRV-1255
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-ChrimsonR-GFP-WPRE-hGH polyA
CAT# AFG-BRV-1254
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-Chronos-EGFP-WPRE-bGH polyA
CAT# AFG-BRV-1236
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-ChETA-EGFP-WPRE-hGH polyA
CAT# AFG-BRV-1203
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-CheRiff-eGFP-WPRE-bGH polyA
CAT# AFG-BRV-1116
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-Flp-EGFP-WPRE-hGH polyA
CAT# AFG-BRV-1090
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-NLS-Flp-bGH polyA
CAT# AFG-BRV-1089
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-Flp-WPRE-hGH polyA
CAT# AFG-BRV-1088
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-fDIO-Cre-WPRE-hGH polyA
CAT# AFG-BRV-0953
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-mito-Cre-EGFP-WPRE-hGH polyA
CAT# AFG-BRV-0951
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-Cre-P2A-mCherry-WPREs
CAT# AFG-BRV-0950
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-Cre-mCherry-WPRE-hGH polyA
CAT# AFG-BRV-0949
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-Cre-P2A-EGFP-WPRE-hGH polyA
CAT# AFG-BRV-0948
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-EGFP-P2A-Cre-WPRE-hGH polyA
CAT# AFG-BRV-0947
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-Cre-EGFP-WPRE-hGH polyA
CAT# AFG-BRV-0946
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-Cre-WPRE-hGH polyA
CAT# AFG-BRV-0945
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-XCaMP-B-WPRE-hGH polyA
CAT# AFG-BRV-0923
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-XCaMP-R-WPRE-hGH polyA
CAT# AFG-BRV-0922
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-XCaMP-Y-WPRE-hGH polyA
CAT# AFG-BRV-0921
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-DIO-GCaMP7b-Xn-WPRE-hGH polyA
CAT# AFG-BRV-0920
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-GCaMP7b-Xn-WPRE-hGH polyA
CAT# AFG-BRV-0919
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-GCaMP6m-Xn-WPRE-hGH polyA
CAT# AFG-BRV-0918
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAAV® rAAV-hSyn-GCaMP7b-Xc-WPRE-hGH polyA
CAT# AFG-BRV-0917
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD